Understanding the IDO Metabolic Trap Hypothesis

‘Typical IDO2 is protective against ME’ might be a better way around to describe it? IDO2 variants on their own don’t result in ME but people without these variants don’t get ME whatever stressors they encounter? Continue reading

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Review: Rejuvenation Lotion

This post is the first time I have been given the product as part of a product review through the Chronic Illness Bloggers network. Continue reading

Are you Disabled?

On Twitter there have been some interesting discussions this week about disability identity and ME. I think this is worth everyone with ME thinking about. For most of us ME is enduring, substantial & has a significant effect on our life. These are the very requirements of defining a disability. Continue reading

Paradoxical Research Funding

An argument has erupted this week between UK psychologists and funders that has relevance for the problems we face with ME research. Could a common purpose create a very unexpected alliance to improve appropriate allocation of research funding? Continue reading

Review: Can Post-Exertional Malaise make a Placebo Effect seem like a Nocebo?

Does Post-Exertional Malaise lead to unusual Placebo Effects in ME that seem more like Nocebo? This post explores my experience of a Placebo controlled experiment. Continue reading

Resource: Walking Problems

This post includes tips that may help you with walking and muscle problems. Topics covered include mitochondrial function (MitoQ, D-Ribose, AMPK activation), lactic acid, electrolyte balance, autonomic function, pacing and adapting. Please comment on what I’ve missed out. Continue reading